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BIOQUAD OSTEODENX®

OsteoDenx® is a potent bone and joint bio-replenishment that helps support and reinforce a healthy skeletal system. This clinically-proven formula is powered by Syno-PORTIN® Complex, a nutrient target delivery system composed of milk-derived ribonuclease-enriched lactoferrin (R-ELF).
Unlike traditional vitamin/mineral-based supplements, which may not be properly absorbed or integrated, Syno-PORTIN® Complex helps deliver bone and joint nutrients to their specific target site – the synovium.
Accordingly, OsteoDenx® promotes the optimal balance of nutrients within bones and joints, maintains healthy bone mineral density, and reinforces the integrity of joint cartilage. The innovative technology behind OsteoDenx® is backed by multiple US patents.
Health Benefits*
  • Promotes Formation of Healthy Bone Tissue*
  • Supports Healthy Bone Mineral Density*
  • Protects, Lubricates and Cushions Joints*
  • Maintains Joint Flexibility and Mobility*
  • Enhances Absorption of Bone and Joint Nutrients*
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informed-sport-trusted-by-sport-logo-nut

US Patent #7601689

US Patent #8003603

US Patent #8968726

US Patent #9181536

PRODUCT DESCRIPTION

What is OsteoDenx?
OsteoDenx is an exclusive bone and joint health technology – with a unique mechanism of action that provides several health benefits. This advanced formula was granted protection of four US patents. OsteoDenx contains Syno-Portin® Complex, a novel targeted nutrient delivery system based on ribonuclease-enriched lactoferrin (R-ELF). R-ELF is a precisely calibrated mixture of two multi-functional bioactive proteins sourced from milk, specifically lactoferrin and ribonuclease (a.k.a. angiogenin or RNAse types 2 and 4).

R-ELF is a vital component of the synovial fluid that plays an important role in bone growth and repair. The bone and joint health benefits of R-ELF (Active group) was evaluated and compared to calcium/vitamin D supplementation (Placebo group). In an IRB-approved, randomized, double-blind, placebo-controlled human clinical study, participants administered with R-ELF experienced a statistically significant increase in osteoblastic activity (bone formation), optimized bone resorption (bone loss) and demonstrated improvement in joint comfort within six months compared to placebo group. The study results were published in top-tier, peer-reviewed medical journals.
How does OsteoDenx Work?
The skeleton is dynamic system that undergoes continuous remodeling via two opposite processes: i) deposition of minerals (particularly calcium) to maintain bone mineral density (BMD) and ii) withdrawal (resorption) of minerals from its bone matrix to support various bodily functions. Maintaining a balance (homeostasis) of the bone remodeling process is essential for the overall skeletal health, which is dependent on a continuous supply, transport and delivery (collectively known as ‘bio-availability’) of essential nutrients. The body has several pathways to efficiently process and effectively utilize such essential nutrients. OsteoDenx® is designed to reinforce these innate mechanisms for complete bone and joint health.

OsteoDenx® promotes healthy bone turnover (metabolism).*

This patented formula supports both aspects of bone turnover, i.e. bone formation and bone resorption. OsteoDenx® has been clinically-proven to promote the formation of healthy bone tissue and help optimize bone resorption, thereby strengthens the overall bone tissue matrix.

OsteoDenx® helps improve the bio-availability of essential nutrients.*
 
Syno-PORTIN® Complex is an effective target delivery system based on milk lactoferrin and milk ribonuclease (R-ELF).
  • Lactoferrin is the body’s native transport protein that binds to essential transitional metals. Lactoferrin has millions of its putative receptors on the intestinal brush border. Once lactoferrin is bound to a metal, it can transport it across the intestinal barrier via a ‘lock and key’ mechanism – lactoferrin (key) binds to its receptor (lock) and translocates itself (with the bound metal) into the body. OsteoDenx® helps absorb essential nutrients and transports them to their designated target – the synovium.
  • Ribonucleases / RNAse are the body’s native angiogenic factors that promote formation of new blood capillaries. The maintenance of a healthy vascular system is critical for transport of essential nutrients across the body. OsteoDenx® is the only product formulated with milk-ribonuclease to reinforce the circulatory route for optimal distribution of essential nutrients. It also contains Vitamin K and Resveratrolfor optimal vascular health.
OsteoDenx® helps in the maintenance of healthy joints.*

Articulations (joints) naturally undergo ‘wear and tear’ during physical movement. In response, the body has to continuously replace cartilage and synovial fluid to protect the joints. Specifically, the body produces collagen (protein) and glycosaminoglycan (GAG) polymers to support joint function. OsteoDenx® is rich in collagen peptides and manganese to promote healthy cartilage formation and joint health.

OsteoDenx® helps protect bone-joint tissue from oxidative damage.*

Bone turnover is an energy-intensive metabolic process that generates tissue-damaging oxidative free radicals. OsteoDenx® contains a complete mixture of antioxidants, including milk proteins (lactoferrin and ribonuclease), plant-extracts (Boswellia and Resveratrol), minerals (copper and selenium) and vitamins (D3 and K1) Collectively, these antioxidant synergists protect the bones and joints from free radical damage.
Why should I take OsteoDenx?
Bone and joint problems are common that affects people of all age, sex, diet, lifestyle, etc. Many individuals, let alone athletes, have experienced bone and joint problems personally or know someone who has – be it a sprain, fracture, twist, etc. Even a healthy individual will inevitably suffer from a compromised skeletal system due to progressive deterioration with age (in fact, humans reach their peak bone mass by the age of thirty). Therefore, it is important to take proactive steps to ensure a healthy skeletal system, following an active lifestyle and a complete diet.

  • Active Lifestyle: The strength of bones and joints depend on a ‘use it or lose it’ principle. If an individual is sedentary or obese, such condition may lead to a weak skeletal system. On the other hand, if an individual overuses bones and joints causing excessive ‘wear and tear’, then he or she might face similar consequences. Regular and moderate weight-bearing exercise is recommended to avoid such scenarios.

  • Complete Diet: Diet provides the energy and ‘building blocks’ to maintain the skeletal structure and function. The body has specific pathways that convert these dietary ‘building blocks’ into its own multi-functional regulatory molecules known as bio-replenishments. Lactoferrin and ribonucleases are bio-replenishments naturally produced inside the body. An individual normally produces these molecules to meet the physiological demand (i.e. bio-replenishment levels are in balance). However, due to various factors such as poor diet, stressful lifestyle, aging, an individual may show a decline in bio-replenishment synthesis and/or utilize in excess. Overtime, this can lead to bio-replenishment deficiency, manifesting as various health problems.
It can be challenging to keep an active lifestyle and complete diet all the time. Therefore, adding OsteoDenx® to a daily nutritional regimen is a proactive approach to maintain healthy bones and joints.
What's inside OsteoDenx?
Syno-PORTIN® Complex
RNase-enriched Lactoferrin (from milk), Collagen hydrolysate (from fish) and Boswellia (from Boswellia serrata)

Other Active Ingredients
Resveratrol (V. vinifera/P. cuspidatum), Vitamin D3 (as Cholecalciferol), Vitamin K1 (as Phytomenadion), Folate (as Folic acid), Copper (as sulfate), Manganese (as sulfate) and Selenium (as Selenomethionine)

Other Ingredients
Vegetable capsule (HPMC), Sodium bicarbonate, Magnesium stearate and Silicon dioxide
Recommend Dosage for Athletes
Two capsules of 60 mg/day each (120 mg/day total) by mouth is the suggested dosage as part of regular replenishment for a healthy individual with an active lifestyle. However, depending upon the intensity of your training, age and health-status, increasing the dosage to 2 or 3 capsules per day could benefit certain individuals.

It can taken anytime of the day, with or without food, but the optimal time is before bed since mineral absorption activity is highest during sleep.

PRODUCT QUALITY

How to Choose The Right Lactoferrin Supplement

All lactoferrin supplements are not created equal
As a result, the potency and effectiveness of lactoferrin supplements can vary significantly. A low quality or ‘denatured’ lactoferrin supplement may actually harm the body rather than doing any good.
This short video covers ‘How to Choose the Right Lactoferrin Supplement’ and how Lactoferrin Gold 1.8® ensures you receive the highest possible quality standards available globally.

PRODUCT FEATURES & BENEFITS

Approved for Athletes

Informed-Sport is an independent third-party quality assurance program serving the sports nutrition industry. Every batch of OsteoDenx® is tested for banned substances; products undergo rigorous testing at an ISO17025 accredited lab to provide the highest level of assurance that they are safer for athletes to use.

Clinically-Proven Results

In an IRB-approved, randomized, double-blind, placebo-controlled human clinical study, participants supplemented with R-ELF (the active in OsteoDenx®) experienced a statistically significant increase in bone formation, optimization in bone resorption and demonstrated an improvement in joint comfort within six months.

Total Bone & Joint Support

OsteoDenx® is an exclusive bio-replenishment clinically-proven to support the entire skeletal system. It works differently than other generic vitamin or mineral supplements. Only OsteoDenx® reinforces the body’s innatemechanisms to help build healthy bone tissue and promote optimal joint mobility, naturally.

Patented Technology

OsteoDenx® is the only bone and joint formula with Syno-PORTIN® Complex, a novel nutrient target delivery system protected by multiple US patents. This unique product formula contains asynergistic blend of milk proteins (R-ELF), phyto-antioxidants, collagen peptides and essential vitamins and minerals – which provide maximum health benefits.

All Natural Formula

OsteoDenx® is made of all natural, premium quality ingredients. The formula contains NO lactose, gluten or soy. The R-ELF in OsteoDenx® is isolated from pure milk sourced from healthy dairy cows. The government certifies these cows are hormone-free, antibiotic-free, non-GMO, non-transgenic and raised freely in a clean, green pasture environment.

Suitable for All Athletes

OsteoDenx® is can be safely used by all athletes. The recommended dose regimen can be adjusted based on a person’s specific diet, lifestyle and needs. If a person is sensitive or allergic to any of the product ingredients, or has any medical condition or concern, they should consult their health care provider before taking any dietary supplement.

Frequently Asked Questions (FAQs)

What are Bio-Replenishments?
Bio-replenishments are bio-active molecules that are produced and expended by the body on a regular basis. Examples include insulin, hormones, lactoferrin and ribonuclease. These molecules regulate our metabolism and maintain physiological balance or ‘homeostasis’. Any deficiency or dysfunction of bio-replenishments manifests as disorder(s), disease(s) or death.
What is OsteoDenx?
OsteoDenx is an exclusive bio-replenishment that supports the entire skeletal system. The formula contains Syno-PORTIN Complex, a novel nutrient target delivery system powered by ribonuclease-enriched lactoferrin (R-ELF). It helps absorb, transport and deliver essential nutrients to the bone and joint space (aka. the synovium).
What is ribonuclease-enriched lactoferrin (R-ELF)?
Lactoferrin and ribonuclease are proteins naturally produced inside the body. They co-exist in milk and other biological fluids as key regulatory molecules with specific role in various physiological pathways. From a skeletal system perspective, the proteins combined help promote healthy bone turnover and maintain healthy joints.
What makes OsteoDenx unique?
The technology in OsteoDenx is backed by over 30 years of scientific research, 2 human clinical studies with published results and 4 US patents. OsteoDenx is distinct from other generic vitamin or supplements because it actually helps support the body’s own process of forming new bone and lubricating joints. In complementing this natural building and repair process, OsteoDenx® can help promote strong, healthy bones and joints throughout life.*
How is OsteoDenx made?
OsteoDenx is manufactured in Europe in a government certified manufacturing facility that meets current good manufacturing practices (cGMP) standards. Only the highest quality ingredients are sourced and third-party tested for purity. All ingredients also undergo meticulous testing at each stage of the production process, resulting in the safest, highest quality product.
What are the side effects from taking OsteoDenx?

No side effects have been reported with OsteoDenx. However, if any discomfort is noticed by consuming OsteoDenx immediately stop taking the product and consult your primary health care provider.

Can individuals with lactose-intolerance take OsteoDenx?
Yes. There is NO lactose sugar in OsteoDenx.
Can pregnant women take OsteoDenx?
Yes, a pregnant woman may take OsteoDenx. However, a woman with any medical condition (including pregnancy) should consults her with health care provider before using this or any supplement.
Can children take OsteoDenx?
Yes, a child above the age of 4 may take OsteoDenx. However, it is advisable to consult with the child’s health care provider before use of this or any supplement.
Should OsteoDenx be taken with food or on an empty stomach; daytime or bedtime?
It is recommended to take OsteoDenx at bedtime with or without food (because the mineral metabolism is most active during sleep).
Can OsteoDenx be taken with other dietary supplements?
Yes. OsteoDenx can be taken in conjunction with other dietary supplement(s).
Should OsteoDenx not be taken with certain types of medications?
If a person has any medical condition (under any medication), it is advisable to consult with that person’s health care provider before use of this or any supplement.
Can OsteoDenx be taken together with alcoholic beverages?
No. However, OsteoDenx can be spaced at least 12 hours before or after consumption of an alcoholic beverage.
Can OsteoDenx be taken together with hot beverages or foods?
No. However, OsteoDenx is relatively stable at high temperatures and it is OK to consume this protein supplement with warm foods.
* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent disease.
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